Gynaecological oncology research
We are a leader in local, national and international gynaecologic cancer research encompassing basic science, histopathology, molecular genetics, surgical innovation, peri-operative care, medical oncology, psycho-oncology and survivorship.
Given the large number of patients seeking treatment for gynaecological cancers at St John of God Subiaco Hospital (the hospital treats about half of all Western Australian gynaecological cancer cases), we are well placed to undertake translational research.
- Gynaecological cancers, including ovarian, endometrial, cervical and uterine cancers, are the third most commonly diagnosed cancer in women in Australia.
- Gynaecological cancer research will help improve outcomes and survival rates as well as improve detection, education and quality of life for gynaecologic cancer survivors.
- Attracting the best clinicians and research scientists to our group will deliver new and improved treatments to patients.
- Improving quality of life for ovarian cancer survivors, particularly identifying and reducing the effects of cancer and long-term physical and psychological effects of treatment.
- Individuals at high risk for gynaecological cancers including women who carry BRCA1/2 gene faults and patients with Lynch Syndrome.
- Early detection of ovarian cancer.
- Population health studies and epidemiology of gynaecological cancers in Western Australia using data linkage.
- Treatment of cervical dysplasia (pre-cancerous changes involving the uterine cervix).
- Genetic alterations in rare gynaecological malignancies as potential targets for novel therapies.
- Surgical trials.
- The role of minimally invasive techniques, including robotic-assisted surgery, in the treatment of gynaecological cancers.
Dr Paul Cohen MD
Dr Stuart Salfinger
Dr Jason Tan
Dr Raj Mohan
Dr Adeline Tan
Professor Colin Stewart
Dr Andrew Dean
Dr Martin Buck
Dr Tarek Meniawy PhD
Post-doctoral Research Fellow
Dr Aime Munro PhD
Senior Scientist in Charge, Molecular Oncology
Dr Kerryn Garrett PhD, FFSc (RCPA)
Senior Molecular Scientist
Dr Marie Rye PhD
Below is a select list of our publications
Tucker P, Bulsara M, Salfinger S, Tan J, Green H, Cohen P, January 2016, Prevalence of Sexual dysfunction after risk reducing salpingo-oophorectomy Gynecologic Oncology Volume 140, Issue 1, Pages 95–100
Acton J, Salfinger S, Tan J, Cohen P, January 2016 Outcomes of total laparoscopic hysterectomy using a 5mm vs. 10mm laparoscope: A randomized control trial Journal of Minimally Invasive Gynecology Volume 23, Issue 1, Pages 101–106
Tan A, Stewart C, Garrett K, Rye M, Cohen P, December 2015 Novel BRAF and KRAS mutations in papillary thyroid carcinoma arising in struma-ovarii Endocrine Pathology Volume 26, Issue 4, pp 296-301
Tan A, Salfinger S, Tan J, Cohen P, August 2015 Morcellation of occult uterine malignancies: A single institution retrospective study Australian and New Zealand Journal of Obstetrics and Gynaecology Volume 55, Issue 5, Pages 503–506
Goh J, Mohan GR, Ladwa R, Ananda S, Cohen P, Baron-Hay S, December 2015 Frontline treatment of epithelial ovarian cancer Asia Pacific Journal of Clinical Oncology Volume 11, Issue Supplement S6, pages 1–16
Munro A, Powell RG, Cohen P, Bowen S, Spilsbury K, O'Leary P, Semmens JB, Codde J, Williams V, Steel N, Leung, Yee, January 2016, Spontaneous regression of CIN2 in women aged 18–24 years: a retrospective study of a state-wide population in Western Australia Acta Obstetricia et Gynecologica Scandinavica Vol 95, No 3, Page 291-298
Cohen PA, Nichols CB, Schofield L, Van Der Werf S, Pachter N, June 2016, Impact of Clinical Genetics Attendance at a Gynecologic Oncology Tumor Board on Referrals for Genetic Counseling and BRCA Mutation Testing, International Journal of Gynecological Cancer 26(5):892-7
Tucker P, Bulsara M, Salfinger S, Tan J, Green H, Cohen P, July 2016, Discussing sexuality with women considering risk-reducing salpingo-oophorectomy: An international survey of current practice in gynecologic oncology, International Journal of Gynecological Cancer Epub ahead of print
Stewart C, Frost F, Leake R, Mohan GR, Tan J, December 2015, Foamy gland changes in gastric-type endocervical neoplasia, Pathology 47(7):653-8
Cohen PA, Flowers N, Tong S, Hannan N, Pertile MD, Hui L, August 2016, Abnormal plasma DNA profiles in early ovarian cancer using a non-invasive prenatal testing platform: implications for cancer screening, BMC Medicine 24;14(1):126
You may be interested in