Intensive care research at Subiaco

In addition to contributing to national and international clinical trials, members of the Intensive Care Unit (ICU) Research Group have developed and published multiple studies conceived to address the specific needs of patients admitted to one of the busiest private ICUs in Australia.

The St John of God Subiaco Hospital ICU is one of the busiest private ICUs in Australia. St John of God Hospital Subiaco admitted 1,586 adult patients to the Intensive Care Unit 2018/2019.
Our clinical research has the potential for broad benefits, while at the same time focuses on issues of particular importance to patients treated at our hospital. 



The focus has been on particular areas of interest and expertise including the use of clinical quality registry data to investigate the processes and outcomes associated with bariatric surgery, delivering the highest quality care to patients undergoing cardiothoracic surgery, support of the next of kin of patients admitted to the ICU, investigating the effect of probiotic therapy on nosocomial infection and other outcomes in critical illness, and the importance of sleep in recovery from critical illness.

The Intensive Care Research Group is also involved in REMAP-CAP, led by Prof Steve Webb as the Principal Investigator. This is an international adaptive randomised controlled trial (RCT) of treatments for community-acquired pneumonia that also includes patients with COVID-19.
Consultant Intensivists
• A/Professor Kwok Ho
• Dr Ed Litton: Research Fellow and Consultant Intensivist
• Dr David Morgan: Head of Department ICU and Consultant Intensivist
• Professor Steve Webb: Director of Clinical Trials St John of God Subiaco Hospital and Consultant Intensivist

Research Officers
Janet Ferrier
Lesley Kemp
Morgan, D., Ho, K. M., & Platell, C. (2019). Incidence and Determinants of Mental Health Service Use After Bariatric Surgery. JAMA psychiatry, 77 (1), 60–67. Advance online publication. jamapsychiatry.2019.2741

Litton, E., Latham, P., et al. (2019). Safety and efficacy of erythropoiesis-stimulating agents in critically ill patients admitted to the intensive care unit: a systematic review and metaanalysis. Intensive Care Medicine, 45 (9), 1190–1199.

Litton, E., Anstey, M., Broadhurst, D., Chapman, A. R., Currie, A., Ferrier, J., et al. (2020). Study protocol for the safety and efficacy of probiotic therapy on days alive and out of hospital in adult ICU patients: the multicentre, randomised, placebo controlled Restoration Of gut microflora in Critical Illness Trial (ROCIT). BMJ open, 10 (6), e035930. doi. org/10.1136/bmjopen-2019-035930

Morgan, D., Platell, C., & Ho, K. M. (2020) The incidence and determinants of bariatric reoperations: a population-based cohort study. Surgery for obesity and related diseases: official journal of the American Society for Bariatric Surgery, 16 (5), 663–669.