Associate Professor Sharma completed his paediatric specialty training through the Royal Australasian College of Physicians (RACP) in Melbourne and Perth. He then moved to Toronto, Canada, where he finished his clinic fellowship in paediatric gastroenterology and hepatology at the Hospital for Sick Children, University of Toronto.

Associate Professor Sharma has a special interest in paediatric inflammatory bowel diseases, including Crohn's disease, ulcerative colitis, eosinophillic esophagitis, coeliac disease, gastroesophageal reflux disease, nutrition and liver conditions in children.

Associate Professor Sharma is fully accredited for paediatric endoscopy and colonoscopy procedures. He also provides 24-hour pH study for chronic reflux patients and multidisciplinary bowel management service.

Associate Professor Sharma treats both public and private patients at St John of God Murdoch Hospital and St John of God Midland Public Hospital. Ajay has published many articles in high impact journals and is also currently Chair of the Gastroenterology Society of Australia (GESA) Paediatric Network (since November 2020).