Colorectal research

The Colorectal Cancer Research Group aims to improve survival outcomes for patients with colorectal cancer.

Established in 2006, we provide optimal medical and surgical management to colorectal cancer patients, integrated with laboratory and clinical research to provide evidence-based care. 

  • Colorectal cancer is the third most commonly diagnosed cancer in Australia with a survival rate of 68 per cent.
  • Our research aims to understand all aspects of colorectal cancer to provide comprehensive, evidence based care for patients.

We focus on improving surgical outcomes and survival in patients presenting with colorectal neoplasia and why patients react positively or negatively to treatment to better select treatment options and improve survival rates.

Our past and present research interests include:

  • epidemiology of colorectal cancer
  • surgical and survival outcomes after colorectal cancer surgery
  • genetic and histological markers for prognosis 
  • cancer clinical trials in colorectal surgery
  • population-based screening program for familial bowel cancer in WA
  • identification of factors which may predict early stage colon cancer.
We have two clinical trials underway and are currently recruiting participants.
Director of Colorectal Research Group
Professor Cameron Platell

Consultant Pathologist
A/Professor Christine Hemmings

Clinical Nurse Co-ordinator
Cheryl Penter

Postdoctoral Research Fellow
Dr Melanie McCoy

Research Staff
Timothy Miller
Tracey Lee-Pullen
Stephanie Austin
Chidozie Anyaegbu
Janelle Leadbitter
Maria Beilin

Medical Oncologists
Dr Daphne Tsoi
Dr Thomas Van Hagen
Dr Ru-Wen Teh
Dr Tim Clay

Associate Investigators
Mr Michael Levitt
Mr Patrick Tan
Dr Paul Salama
Dr Kerryn Garrett
Dr Marie Rye
Mr Nigel Barwood 
Mr Gregory Makin 
Dr Sanjay Mukhedkar 
Dr Kynan Feeney 

Below is a select list of our publications

Teloken PE, Spilsbury K, Platell C, Committee BO. Analysis of mortality in colorectal surgery in the Bi-National Colorectal Cancer Audit. ANZ journal of surgery. 2016 Jun;86(6):454-8. PubMed PMID: 27091111.

Williams AM, Allen J, Zeps N, Pienaar C, Bulsara C, Monterosso L. Consent to Donate Surgical Biospecimens for Research: Perceptions of People With Colorectal Cancer. Cancer nursing. 2016 May-Jun;39(3):221-7. PubMed PMID: 26050142.

Hardcastle, SJ, Maxwell-Smith, C, Zeps, N, Platell, C, O’Connor, M & Hagger, M.S (2016). A Qualitative Study Exploring Health Perceptions and Factors Influencing Participation in Health Behaviors in Colorectal Cancer Survivors. Psycho-Oncology 2016 Mar 3 [Epub ahead of print].  PubMed PMID: 26935994

Teloken PE, Ransom D, Faragher I, Jones I, Gibbs P, Platell C. Recurrence in patients with stage I colorectal cancer. ANZ journal of surgery. 2016 Jan-Feb;86(1-2):49-53. PubMed PMID: 26235683.

McCoy MJ, Hemmings C, Miller TJ, Austin SJ, Bulsara MK, Zeps N, et al. Low stromal Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer. British journal of cancer. 2015 Dec 22;113(12):1677-86. PubMed PMID: 26645238. PubMed PMID: 26645238

McCoy MJ, Hemmings C, Hillery S, Penter C, Bulsara MK, Zeps N, et al. Neoadjuvant chemoradiotherapy for rectal cancer: how important is tumour regression? ANZ journal of surgery. 2015 Dec 3. PubMed PMID: 26631340.