Breast cancer research
Breast cancer research at St John of God Health Care focuses on improving the health, care and lifestyles of those affected by breast cancer. We do this in collaboration with valued partners, such as universities, research institutes and Cancer Council WA.
- 1 in 8 Australian women will be diagnosed with breast cancer before the age of 85. Over 15,000 women per year.
- 150 men will be diagnosed with breast cancer every year.
- Survival rates for this disease continue to improve – with research supporting early detection and better treatment.
- Medical and surgical oncology clinical trials - both locally initiated studies and national and international trials. These trials examine aspects of breast cancer prevention, diagnosis, treatments, post treatment, survivorship, fertility, end of life care, drugs development, and translation of research into practice.
- Supportive care research - such as exercise intervention and enabling young breast cancer survivors to start families.
- Health services research that can help deliver more equitable and effective cancer care to Western Australians.
- Translational research made possible by our comprehensive breast cancer research data bank, known as a biobank. We undertake this research in collaboration with national and international researchers.
Prof Christobel Saunders
Dr Daphne Tsoi
Dr Andrew Dean
Dr Ru-Wen Teh
Dr Tim Clay
Breast Surgeons/Senior Clinical Lecturers
Dr Lee Jackson
De Wen Chan Yeow
Dr Bridget Cooke
Dr Niloufer Johansen
Below is a select list of our publications.
Meiser B, Quinn VF, Gleeson M, Kirk J, Tucker KM, Rahman B, Saunders C et al, ‘When knowledge of a heritable gene mutation comes out of the blue: treatment-focused genetic testing in women newly diagnosed with breast cancer’, European Journal of Human Genetics, 2016 Jun 22, doi: 10.1038/ejhg.2016.69
Zdenkowski N, Forbes JF, Boyle FM, Kannourakis G, Gill PG, Bayliss E, Saunders C et al, ‘Observation versus late reintroduction of letrozole as adjuvant endocrine therapy for hormone receptor positive breast cancer (ANZ0501 LATER): An open-label randomised controlled trial’, Annals of Oncology, 2016 Feb 9, pii: mdw055
Kennedy KM, Chin L, McLaughlin RA, Latham B, Saunders CM et al, ‘Quantitative micro-elastography: Imaging of tissue elasticity using compression optical coherence elastography’, Nature, 2015 Oct 27, Vol 5, p. 15538, doi 10.1038/srep15538
Cuzick J, Sestak I, Forbes JF, Dowsett M, Knox J, Cawthorn S, Saunders C et al, ‘Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial,’ The Lancet, 2014 Mar 22, 383(9922), doi: 10.1016/S0140-6736(13)62292-8
Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph DJ, Keshtgar M, Flyger HL, Massarut S, Alvarado M, Saunders C et al, ‘Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial’, Lancet, 2014 Feb 15, 383(9917):602, doi 10.1016/S0140-6736(13)61950-9
Fritschi L, Erren TC, Glass DC, Girschik J, Thomson AK, Saunders C et al, ‘The association between different night shiftwork factors and breast cancer: a case-control study,’ British Journal of Cancer, 2013 Oct 29, 109(9):2472-80, doi: 10.1038/bjc.2013.544
McLaughlin RA, Scolaro L, Robbins P, Hamza S, Saunders C et al, ‘Imaging of human lymph nodes using optical coherence tomography: potential for staging cancer,’ Cancer Research, 2010 Apr 1, 70(7):2579-84, doi 10.1158/0008-5472.CAN-09-4062
Ives A, Saunders C et al, ‘Pregnancy after breast cancer: population based study’, British Medical Journal, 2007 Jan 27, 334(7586):194-6B
Hickey M, Saunders CM et al, ‘Management of menopausal symptoms in patients with breast cancer: an evidence-based approach’, The Lancet Oncology, 2005 Sep, 6(9):687-95
Ives AD, Saunders CM et al, ‘The Western Australian gestational breast cancer project: a population-based study of the incidence, management and outcomes’, The Breast, 2005 Aug, 14(4):276-82
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